First off, I have no idea which symptoms specifically will be able to proc the Ultimate Combo. All I know are these things I've noted while playing:
- You must have the Red-Suited Pilot and Red-Nosed Guide abilities. These abilities stem from the Gift Plane ability, an ability which enables the gift planes--duh--that will appear from time to time. These two abilities have red icons, which makes them really hard to miss.
- You will need to have some other Red abilities in order to successfully make the combo activate. The specific transmissions or symptoms you need is what I'm unsure of, but I am quite sure that you need some other red-icon transmissions or symptoms. I've tried playing with only Red-Suited Pilot and Red-Nosed Guide active, the combo didn't even pop-up.
- It takes some time to show up. Like any other combo pop-up
To give you a much clearer idea on which transmissions, symptoms, and abilities you'll need, here's a screenshot of my Disease tree when I got the achievement. I'm lazy, go find the specific things yourself, can't even be bothered to Google, that's how lazy I am right now.
As you can see, I have 8 red-icon thingies evolved before the pop-up showed up.
After some time of waiting, after having several red-icon stuff, this pop-up will appear. Bringing the achievement along with it.
That about does it. Hope you got it. Excuse my laziness, I might have gotten the Sloth symptom from the worm. THE WORM IS ALMIGHTY! ALL PRAISE!
Thanks for reading this guide and as always, Happy Spicy Gaming!
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