Plague Inc: Virus Speed Run

Virus Speed Run Guide

  Welcome to the 2nd speed run guide I have made so far! I had some trouble with this guide mostly due to the fact that the disease type virus has unstable properties. The main problem is the due to the fact that mutations may significantly slow you down. I solved this problem with getting the gene Base Oxidisation due to the fact that now there is a chance that it mutates transmissions which reduces the downside to the viruses property to mutate. It also therefore causes it to evolve unwanted symptoms and turns it into a strength. I would like to note although it only reduces the chances and that there is still a chance of a unwanted symptom to evolve. It is a pretty simple guide and I hoped it helps you! I would like to note that it may not work every time due to several pseudo-random factors in the game play but it should work most of the time.

   Firstly, on to the genetic code for your virus and I will provide an explanation for the reason I picked these genetic sequences to choose for your virus. I would highly recommend you get all of these genes before you play the game as it may be impossible to win using this strategy without it! I would like to remind you that it effects all strategies as it is basically impossible or impossible to my knowledge to get 5 biohazards in speed run without using your genetic code. Do not worry about trying to jot down the genes I listed here because I provided it below anyway.
  1. I recommend ATP Boost due to the fact that pre-evolving coughing, cysts, and abscesses speed up the infection rate allowing us to speed up to the time to win.
  2. I choose Aquacyte due to the fact that it allows us to infect the islands better.
  3. I choose the gene Sympto-stasis due to the fact that it allows us to get additional symptoms without the cost going up. We will use transmissions but by a different way which brings us to the Base Oxidisation gene.
  4. I choose the gene Base Oxidisation gene due to the fact that it actually complements the viruses natural tendency to evolve different trait which causes many people frustation. Better to have evolve transmissions to help us! 
  5. I choose the gene Extremophile due to the fact that it allows our disease to get a minor boost everywhere! Good overall and remains one of the genes I use the most in this spot.
If you just want to see the genetic code just lined up I provided it below.

Genetic Code
  • ATP Boost
  • Aquacyte
  • Sympto-stasis
  • Base Oxidisation
  • Extremophile

 Mutations to De-Evolve List
  • Total Organ Failure
  • Hemorrhagic Shock
  • Internal Haemorrhaging
  • Systemic Infection
Start Mutation De-Evolve List Guide Now!
 1.) I start with this due to the fact that it exhausts all of the DNA points you have and it provides a nice basic infectivity to start the game with which brings us to part 2.

  • Coughing
  • Cysts
  • Abscesses
 2.) Start in the country of China. I am using this country due to the fact that it is easier to infect the countries of Greenland and Iceland which helps a lot in speed run games. The reason for this is because China borders the country of Russia which has a port which sends ships to Greenland allowing easier infectivity of the island.

3.) Seasoned Spicy members will realize that I again fall upon my favorite strategy of using skin lesions to spread your disease. The reason I love this combo so much is due to the fact that it provides significant infectivity without providing any lethality and its relativity low DNA cost makes it a great combo to use in almost every game in my opinion but this is not a strict rule as there are exceptions. A good example of this the fungus plague type as I use Patho-stasis in order to transmit the fungus but that is another story.
  • Rash
  • Sweating
  • Skin Lesions
 3.) Again I will evolve another one of my favorite combos due to the fact that it provides again more infectivity for little cost. I would just like to note that both of these symptoms have effects on the lungs.
  • Sneezing
  • Pneumonia
 4.)  I love and hate this combo due to the fact that it boosts severity and infectivity. The main part that worries me is the fact that severity is a mixed bag. Severity boosts DNA points earned but it also may cause ports to shut down. Diarrhoea is the first symptom in this guide which is evolved on purpose which causes lethality.
  • Nausea
  • Vomiting
  • Diarrhoea
 5.) These symptoms don't increase infectivity by a long shot but it moderately increases severity which I hope will help you get more DNA points.
  • Anaemia
  • Haemophilia
 6.) This will just increase severity and slightly increase infectivity. It was just evolved for the chance for more DNA points.
  • Hyper Sensitivity
 7.) These symptoms obviously vastly increase the infectivity of your virus and its ability to spread on ships and airplanes.
  • Water I
  • Water II
  • Air I
  • Air II
  • Extreme Bioaerosol 
 8.) At this point your virus should be spreading across the globe so it needs everything to survive. That is why these abilites come in. Do not worry about evolving genetic hardening I and genetic hardening II as this is a speed run game and your disease will spread fast enough anyway so it is no problem. Also, spending money on genetic hardening would just be wasting DNA points.
  • Cold Resistance I
  • Drug Resistance I
  • Heat Resistance I
  • Cold Resistance II
  • Drug Resistance II
  • Heat Resistance II
  • Environmental Hardening 
 9.) At this point let your virus become vastly unstable and let it evolve but still follow the guidelines for the mutations until I say so.
  • Viral Instability I
  • Viral Instability II
  • Viral Instability III
10.) Wait until the last island country is infected.

In case you are wondering here is the list of island countries in the game so you can see which ones are not infected yet.
  • Greenland
  • Iceland
  • Carribbean58
  • Madagascar
  • Australia
  • New Zealand
  • New Guinea
  • Indonesia
  • Phillippines
  • Japan
  • UK
If all island countries are infected move on!

11.) Stop following my guideline for mutations and let anything evolve!

End De-Evolve List Guide Now!
12.) At this point evolve these symptoms if they haven't evolved yet!

  • Immune Supression
  • Total Organ Failure
  • Necrosis
  • Hemorrhagic Shock
  • Dysentery
  • Internal Haemorrhaging
  • Systemic Infection 
  • Tumours
  • Fever
  • Inflammation
  • Seizures
  • Pulmonary Fibrosis
  • Pulmonary Oedema
  • Paralysis
  • Coma
 13.) At this point just evolve any symptom left or more transmissions if everyone isn't infected!
  •  Any Symptom or any Transmission!
 14.) You win!

   You're welcome on your win! Remember that this should only be attempted on the speed run mode only and should not be attempted on any scenario or a regular game. How many days did you get? Did this guide help you? Write in the comments below for tips and tricks I should add and how you did using this guide!