Plague Inc.[Submitted Guide] Bacteria Mega-Brutal Guide: 5 Biohazards

This guide has been written and submitted by Crakout.

Spicy's Comment: Another guide for Bacteria Mega-Brutal! Based on the linked screenshots Crakout has provided, this guide was made playing on Plague Inc. Evolved!

So, after 4 hours experimenting, I managed to create a guide on how to get 5 biohazard on Bacteria Mega-Brutal. It was kind of easy, actually, because of this: You have to be REALLY aggressive. Because if the world is aggressive with their regular checks and all the research, you have to be even more aggressive than them. At first, I was only getting 4 biohazards, until I thought i should be more aggressive, and that's what I did.

First, the genes:

  • ATP Boost
  • Genetic Mimic
  • Aquacyte
  • Extremophile
  • Sympto-stasis

First, start in Saudi Arabia, and as soon as you start, buy these in order:
  • Rash
  • Sweating
  • Skin Lesions
  • Coughing
  • Sneezing
  • Pneumonia
  • Nausea
  • Vomiting
  • Cysts
  • Abscesses
  • Hyper sensitivity
  • Anemia
  • Haemophilia

Then we move to some transmissions: Water and Air 1
  • Drug Resistance and Cold Resistance 1
  • Drug and Cold 2
  • Genetic Hardening 1

And for the last transmissions:
  • Water and Air 2
  • Extreme Bioaerosol

Buy the second Genetic Hardening
Now here its a trick, because it seems like the sooner you can buy Necrosis, the score would be better, so buy it as soon as you can.

Now wait for all the islands to get infected, and then it's time for
Note: It doesn't matter if there are still countries uninfected or countries where it seems the people is dying fast, that's why we bought Necrosis.

  • Immune Suppression
  • Total Organ Failure
  • Hemorrhagic Shock
  • Internal Haemorrhaging

The rest of the points should be used in stopping the cure
Start first with the symptoms:
  • Coma
  • Inflammation
  • Seizures
  • Insanity
  • Paralysis

After that, you just buy all Genetic Reshuffles and that's it.
Here its some proof:
I hope this guide helped you and I hope I can give you more guides.
Note: Sorry for my bad English, not my native language (It's not that bad!)
Viva México webones!!


  1. Wow, I didnt thought my guide would be post, Im so happy :D
    Thank you Spicy!

  2. Amazing 5 bios first go :) thanks for the guide