Plague Inc.[Submitted Guide] Simian Flu Mega-Brutal Guide: 5 Biohazard Strategy

This guide has been written and submitted by Sketch. Submit your own written guide to us now via our submit section!

Spicy's comments: The more strategies, the better chances right? Here's a guide submitted by Sketch that helped him get a 4/5 biohazard score on mega-brutal difficulty on the Simian Flu. Please remember to comment and give some feedback on this guide for its improvement.


Sketch’s Simian Flu Mega-Brutal 4 Bio Guide(Outdated)

(This has worked 3/3 times now so I’m submitting. Also, I know; only 4 bios. I am sure that with a little tweaking, it will be 5 and I’ll submit that when I get there if you don’t beat me to it.)
The basic strategy here is to infect the apes first, then the humans. I’ll try to make everything else clear as we progress. Good luck!


Genes: ATP Boost, Aquacyte, Ion Surge, Leadership, and Extremophile


First two very important things…

1. Devolve EVERYTHING until otherwise noted.
2. Normal play speed and pause are your friends now like never before. Be quick to slow down. Every day counts, particularly towards as genetic drift takes hold.

Start in West Africa.
Evolve Simian Neuro-genesis
Switch to Ape view (on the left). We will be focusing on the apes for a while.
Evolve:

• Blood Gift
• Cutaneous Transfer
• Ape Colonies

Start a colony in West Africa.
Evolve:

• Social Cohesion
• Cognitive Shift
• Education

Start Colonies in Central Africa, Sudan, and East Africa as soon as apes are infected there.Evolve:

• Drug Resistance 1
• Genetic Hardening 1 & 2
• Water 1
• Water2

Continue to devolve everything, EXCEPT Pharyngitis > Coughing > Pneumonia.
Also, focus on India (in Ape view) and build your next colony there ASAP.
Evolve:

• Air 1
• Fomites 1
• Cold 1
• Fomites 2
• Cold 2

Now, go ahead and pause time because the world’s about to explode and you might need some time to take in the following:

• Continue to devolve all lethal symptoms + Photobia & Neuro-enhancement 1, which you should never allow to evolve.
• The India colony should be done by now. Now focus on Indonesia. Your last colony will go there ASAP. (yes... 88 DNA… it’s worth it, I promise)

Now, evolve Hominidae Bridge and go to NORMAL speed and prepare to pop the red bubbles that appear en masse.
Evolve:

• Air 2
• Extreme Bioaerosol
• Primal Awareness
• Fomites 3

Stop devolving Photobia > Subconjunctival Bleed > Subconjunctival Haemorrhage > Blindness.
Evolve Ape Rampage.

Now the real fun begins. You must take out the Gen-sys labs immediately to have any hope of success. Get in the habit of pausing as soon as they appear because often you will need to zoom in for proper placement and time is of the essence. One time, the cure reached 100% before destroying a lab brought it back down to 92%. Just keep calm and rampage on. ( I am so sorry.)

From now on, you must constantly scan the map for new labs so you can take them out ASAP; leaving even one lab for any amount of time leads to a rapid cure. Good luck.

It is worth noting that genetic drift seems to reverse in the end game. DNA costs almost come down to reasonable levels starting soon.
Evolve if they haven’t already:

• Pharyngitis
• Coughing
• Pnuemonia

(Remember that colony you were supposed to build in Indonesia?)
Evolve Organized Travel.

Soon, drones will come for your colonies. You don’t have to leave the country, but you do need to move out of the blue circle ASAP every time to preserve your colonies (DNA stream). Once again, good luck.


Now we probably wait just a bit. When your least infected country hits 5% infection, stop devolving everything EXCEPT Neuro-enhancement 1.
Evolve if they haven’t already:

• Photobia > Subconjunctival Bleed > Subconjunctival Haemorrhage > Blindness
• Headache > Fever > Coma (same run hit this at 99% cure; have faith)

Congratulations, you’re on your way to the Planet of the Apes. From now on, evolve whatever lethal symptom floats your boat, though you should tend towards the more lethal ones.

Stats for the latest game:

Name: SiMega

Time: 1312 days

Cure: 93%

Score: 76,390

4 Bios

I hope this worked for you. Thanks for reading.

- Sketch

Sketch’s Simian Flu Mega-Brutal 5 Biohazard Guide

The basic strategy here is to infect the apes and then use them to infect the humans. I’ll try to make everything else clear as we progress. This guide is proven 5 Bios with four labs having spawned in uninfected countries. Whether you get 4 or 5 Bios depends on your ability to manage Gen-Sys labs and drones. Here we go!

VIDEO GUIDE

Use the following genes:

• ·         ATP Boost – Genetic drift makes early DNA valuable.
• ·         Aquacyte – Islands are tough to infect.
• ·         Ion Surge – Devolving Neuro-Enhancement is expensive.
• ·         Leadership – Quick colonies and cheap abilities.
• ·         Extremophile – Because there isn’t one for cold.

First two very important things:

1. ·         Devolve the first four symptoms, no matter what they are. Then continue to devolve all lethal symptoms (including Fever for now) + Photobia and Neuro-Enhancement 1 (which you should never allow to evolve).
2. ·         Normal play speed and pause are your friends now like never before. Be quick to slow down. Every day counts, particularly before and as genetic drift takes hold. I cannot emphasize this point enough; it can be the difference between 4 and 5 Bios.

1)      Start in West Africa.

2)      Evolve Simian Neuro-genesis. Switch to Ape view (on the left). We will be focusing on the apes for a while.

3)      Evolve:

• ·         Blood Gift
• ·         Cutaneous Transfer
• ·         Ape Colonies

4)      Start a Colony in West Africa.

5)      Evolve:

• ·         Social Cohesion
• ·         Cognitive Shift
• ·         Education
• ·         Primal Awareness

6)      Start Colonies in:

• ·         Central Africa
• ·         Sudan
• ·         East Africa

7)      Evolve:

• ·         Drug Resistance 1
• ·         Genetic Hardening 1 & 2
• ·         Water 1
• ·         Water2

8)      Allow Fever to evolve. Continue to devolve all other lethal symptoms + Photobia and Neuro-Enhancement 1.

9)      Evolve Ape Rampage as soon as the “<SiMega> escaped from Gen-Sys lab” message pops up.

10)   Build Colonies in China and India there as soon as Apes are infected. In the meantime, evolve the following:

• ·         Air 1
• ·         Air 2
• ·         Cold 1
• ·         Cold 2

·         Ape Rampage if not already evolved.

11)   Use Ape Rampage to attack Gen-sys labs immediately to have any hope of success:

·         Get in the habit of pausing as soon as they appear because often you will need to zoom in for proper placement and time is of the essence.

·         If the lab spawns where there are no infected Apes, wait until it goes to an infected country.

·         From now on, you must constantly scan the map for new labs so you can take them out ASAP. This can be another difference between 4 and 5 Bios. Good luck!

12)   Evolve Organized Travel.

·         Soon, drones will come for your colonies. Use Organized Travel to move out of the blue circle ASAP every time to preserve your colonies (DNA stream). This can be another difference between 4 and 5 Bios. Once again, good luck!

13)   Now, go to NORMAL speed and prepare to pop the red bubbles that appear en masse.

14)   Evolve:

• ·         Hominidae Bridge
• ·         Extreme Bioaerosol
• ·         Fomites 1
• ·         Fomites 2
• ·         Fomites3

15)   Only devolve Neuro-Enhancement 1.

16)   Evolve the following if they haven’t already:

• ·         Pharyngitis
• ·         Coughing
• ·         Pneumonia
• ·         Photobia
• ·         Subconjunctival Bleed
• ·         Subconjunctival Haemorrhage
• ·         Blindness
• ·         Headache
• ·         Fever
• ·         Coma
• ·         Genetic Reshuffle 1
• ·         Hardened Reshuffle
• ·         Genetic Reshuffle 2.

17)   In the unlikely event that you have surplus DNA, it goes into lethal symptoms.

18)   Welcome to the 5 Biohazard Mega Brutal Planet of the Apes.

Thanks for reading!

-          Sketch