Plague Inc. Teleportation Scenario: Bacteria Mega-Brutal Guide(3 Biohazards)

Playing Bacteria in the teleportation scenario is kind of like just playing a normal game of Bacteria. Although the teleport pop-up still happens, the game is still pretty doable with the right evolutions.

I have been unable to avoid the teleportation pop-ups causing less infectivity in certain countries. What I was able to do though was to completely ignore those pop-ups. Yes I know, it sounds stupid, but I was able to get a 3 biohazard score without paying too much attention to those pop-ups.

If you have no idea what those teleport pop-ups does, well it makes the origin country have significantly lower infectivity. I was able to counter that by evolving certain transmissions that helped boost the infection rates back to normal. I have no idea whether it's part of the game or I just had a lot of infectivity when doing just that.

I've tested this strategy out multiple times just to make sure I'm not getting lucky. Experimenting with the evolution order several times and making sure I'm evolving the right stuff to maximize the success of getting 3 biohazards. Here's the stats on my last 4 games with this strategy.

I'll get on with the guide now.


  • ATP Boost
  • Aerocyte
  • Sympto-Stasis
  • Genetic Mimic
  • Extremophile

1.) Before starting your plague, evolve Rash and Sweating. Then start your Bacteria plague in Saudi Arabia.

2.) Evolve the following in this order as soon as you get the DNA.
  • Skin Lesions
  • Air 1 & 2
  • Water 1
  • Necrosis
Yeah. Early Necrosis because we're hardcore. Continue evolving.
  • Drug Resistance 1
  • Cold Resistance 1 & 2
  • Coughing
  • Pneumonia
  • Sneezing
  • Water 2
  • Extreme Bioaerosol
  • Cysts
  • Abscesses
  • Hypersensitivity
  • Drug Resistance 2
TIP: Devolve the following if they mutate: Hemorrhagic Shock, Systemic Infection, Internal Haemorrhaging, and Tumours. Remember this until the end.

3.) Right after evolving Necrosis, maybe even after Cold Resistance 1, some countries will begin teleporting. In my experience, it's just a maximum of 3 countries, the worst being China if they teleport. I lose every game I had when China teleported. Continue by evolving the following:
  • Paralysis
  • Coma
  • Total Organ Failure
  • Insomnia
  • Paranoia
  • Seizures
  • Insanity
  • Nausea
  • Vomiting
  • Pulmonary Oedema
  • Diarrhoea
  • Dysentery
That does it for symptoms, we are not going to need any more. Remember to devolve the symptoms I've mentioned above if they mutate, because we don't want to kill too quickly when the teleport-origin countries are left semi-infected.

4.) At this point, we are now trying to cope with the teleport-origin countries' low infection rates. Basically, what I do is evolve and max 3 transmissions:
  • Rat 1
  • Livestock 1
  • Insect 1
  • Rat 2
  • Livestock 2
  • Insect 2
The reason I chose these transmissions is because they cover most of what a country has descriptively. Rat is for urban, livestock for rural, and insect just in case a hot country is left with a low cure infection. These transmissions work best for Korea and Brazil, but for the most part they work quite well anywhere else.

5.) If you have any spare DNA points left, allocate them towards Genetic Re-Shuffles. Now, pray hard and hope that the last 2 or 3 countries don't die off and are completely infected. If it fails, comment here and blame this guide for your failure. It fails then suck it up and try again, if you fail a hundred times then this guide does suck, I'm sorry.

That about does it for this guide, I hope it somehow helped you guys. I really hope it did.

Thanks for reading and if you guys have any tips, please post them below to help your fellow gamers out! And as always, Happy Spicy Gaming!


  1. You were right, China teleported to Greenland and I only scored 2 biohazards, worked well otherwise tho :)

  2. Yo spicy, I get better begin game infectivity when i pick Saudi Arabia, then start with air immediately after the first biohazard bubble. I proceed with the plan until after skin lesions, then I hit cysts, hypersensitivity, before I go to necrosis. Helps get the bug to a rich country a little faster. Anyway as always love the guides. Plague on brother.

  3. Did not manage to score 3 Biohazards from 12 tries...I am fairly sure you can do it with this strategy it's just a matter of little luck - but I am fairly unlucky on that one. Half the time Greenland remained uninfected (stupid coutry! Hate it!) The other half I finished with 2 biohazards

  4. Finally! 3 Biohazards on Mega-Brutal I guess my luck finally turned. On a side note doing this scenario with Nerax does not seem to give you any advantage because they always teleport to a non infected island - If you infect Greenland they teleport to Caribean or Madagascar if you infect 2 out of those they go to New Zealand etc!

  5. did it the 1st time using bacteria speed run

  6. Just going to say one thing...
    F**k Greenland!

    Seriously, lost 90%of my games because it just didn't want to be infected

    Great guide though!