Plague Inc. Russian Nuclear Retaliation Achievement Guide & Walkthrough

This achievement can be unlocked by playing any plague type, even with cheat modes activated. The story behind this achievement is the deep hatred by soon-to-be-elected-by-insane-people President Spalin. The president apparently believes that the plague responsible for killing the entire world was released by Russia. By responding with symptom evolutions on event prompts for this achievement, we are able to not only get Spalin elected but also let her nuke Russia.

Update: Achievement can no longer be unlocked when a cheat mode is active. Necessary updates to this guide will be made soon.

Unlocking this achievement takes a long time. Patience is really required. At some point you might think, "This isn't working" but it will, trust me.

I recommend attempting this achievement while having the Immune Strain activated. As I've already stated, unlocking this will take a long time which means the cure progression will also keep running and you wouldn't want the waiting you did to go to waste. While we're on the subject of recommendations, it is also recommended to attempt this on the Bacteria plague on casual difficulty.

Here are the genes I used to make things a little quicker:
Metabolic Hijack
Aquacyte
Sympto-Stasis
Genetic Mimic
Extremophile

Make sure to devolve any symptom that mutates and, again, be patient.

• Start in China
• Evolve Coughing, Sneezing, Cysts, and Hyper Sensitivity
• In transmissions, evolve Water and Air 1 and 2 then Extreme Bioaerosol
• In abilities, evolve Drug Resistance 1 and 2, Heat and Cold Resistance 1 and 2, then Environmental Hardening.
• Wait until the entire world is infected. (A pop-up saying "there's no more healthy" people appears)
• Evolve the following symptoms: Inflammation, Seizures, and Fever

From this point onwards is where your patience will be tested. Every pop-up we're waiting for takes a long time to appear.

Wait until this pop-up appears:

USA President taken ill

Evolve the Insanity symptom. Once again, wait until the next pop-up appears.

New President of USA selected

Great! Spalin is now president. Back to waiting for another pop-up

USA threatens Russia

After seeing the pop-up above, evolve Paralysis. Then wait for the final pop-up to appear.

USA nukes Russia

The pop-up above signifies that you've unlocked the achievement, Congratulations! I wonder how nuking another country helps stop an epidemic.

You can choose to finish the game or quit, either way you'll still get the achievement.