Plague Inc. Mirror Earth Scenario: Virus Mega-Brutal (3 Biohazards) Guide & Walkthrough

Above: Virus

Above: Know Thy Enemy in Plague Inc
(Note: Do not start in the Ukraine as this simply is meant to represent the world in general.)

 The Virus plague is one of the nine available plagues to finish the Mirror Earth scenario. This guide works with mega-brutal difficulty.  Mirror Earth is a scenario in Plague Inc in which hot becomes cold and the like. In fact it is one of the best scenarios in my opinion of Plague Inc. The trouble like in the other scenarios is to get Greenland and the island countries infected. The majority of the problems again just like bacteria is just getting the island countries infected for the most part. A great place to start out in Mirror Earth is in the United States of America called the USA on the Plague Inc map. For this guide start in the United States. This should if all the island countries get infected net you 3 out of 3 Biohazards on Mega-Brutal. Remember to evolve in the exact order. The guide and walkthrough may not work if you do not follow the exact steps as I will show you. It will also only work for Virus. Do not allow your disease to evolve Total Organ Failure or Hemorrhagic Shock.

Lets start with the gene setup for the guide.
  • DNA Gene: ATP Boost
  • Travel Gene: Native Biome
  • Evolution Gene: Sympto-stasis
  • Mutation Gene: Genetic Mimic
  • Environment Gene: Extremophile
 1.) Before we begin to infect the United States of America (USA on map) we will evolve.
  • Coughing
  • Rash
 2.) For this guide please now infect the USA. Now that the USA has begun to be infected we shall continue to evolve in this exact order. As I said in the heading before evolve in this exact order. If you disease evolves any symptom that my guide tells you to evolve skip it if it already has been evolved.
  • Sweating
  • Skin Lesions
  • Sneezing
  • Cysts
  • Abscesses
  • Pneumonia
  • Nausea
  • Vomiting
  • Hyper Sensitivity
  • Anaemia
  • Haemophilia
  • Insomnia
  • Paranoia
Your disease should now be spreading across the world. It is now time to evolve transmissions.
  • Water I
  • Water II
  • Air I
  • Air II
It is now time to evolve abilities. 
  • Drug Resistance I
  • Drug Resistance II
  • Cold Resistance I
  • Heat Resistance I
  • Cold Resistance II
 It is again time to evolve symptoms.
  • Diarrhoea
  • Pulmonary Oedema
  • Pulmonary Fibrosis
 As the cure research will begin to go up it is time to evolve both genetic hardenings in order to slow down the current research rate.
  • Genetic Hardening I
  • Genetic Hardening II
 Once all of the island countries have been infected please evolve these symptoms and abilites below. At this point allow your disease to evolve total organ failure and hemorrhagic shock.
  • Necrosis
  • Dysentery
  • Viral Instability I
  • Heat Resistance II
At this point it is recommended that you crank open the lethality so now evolve.
  • Total Organ Failure
  • Hemorrhagic Shock
At this point slow down the cure.
  • Paralysis
  • Coma
  • Genetic Reshuffle I
  • Genetic Reshuffle II
  • Genetic Reshuffle III
 At this point you have won! You should get around 800,000 and 310 days. For cure research you should get around 10 percent complete. If it did not work just try again and it should work. If you liked this guide and want to read more feel free to read more. This guide was made by Jake. I am currently making guides for Spicy in areas such as game guides for Plague Inc. and game reviews such as for the famous dystopian world of Bioshock and the blocky world of Minecraft.


  1. It works great! And also works (better) for Who cares scenario. Thanks.

  2. Works for Created equal, too. Start in China.

  3. wow This is great! by far the easiest game I've played. 267 days and 7% cure

  4. Lol, that guide is rock-solid... First try and epic win. =) thx again, oh mighty Spicy! o/