Plague Inc: Bacteria Speed Run

Bacteria Speed Run Guide

   Bacteria speed run is pretty easy to get 5 biohazards compared to the other plague types. Our speed run strategy isn't majorly altered from our mega-brutal guide for bacteria compared to most other plagues due to the the bacteria type plagues' symptoms being very useful in this mode. There is a chance for your disease to get spotted and the ports go down but this is a necessary as we have to get 5 biohazards in the speed run special mode. This is not for getting a high score and should only be used in the special mode speed run. If a symptom evolves feel free to de-evolve the mutated symptom.

 Start-Up Instructions:
(Alternately if this doesn't work as this is only for the IOS just go on speed run and skip to the genetic code part below.)

  1. Go to main menu of Plague Inc or start the app if you currently not on. 
  2. Hit Play
  3. Hit Speed Run 
  4. Choose Bacteria 
  5. At this point you should see your high scores for speed run for the plague type bacteria. Now hit Play.
  6. Name your plague in Plague Inc anything you like.
  7. Use the exact genetic code I show you below and hit play.
  8. Hit Start
Genetic Code
  • ATP Boost
  • Aquacyte or Native Biome
  • Sympto-Stasis
  • Base Hydrolysis
  • Extremophile
1.) Evolve these symptoms before you infected the country I specify in part 2 of the guide. This may save a day or two compared to if you infected the original country you are going to infect first.
  • Coughing
  • Cysts
  • Abscesses
2.) Start in the country of India.

3.) The reason we are now going to evolve the somewhat dull infection-wise symptom rash is because it leads to the very infectious skin lesions symptom which is a huge advantage as it boosts the infectivity massively only for around 7 DNA points compared to 26 DNA for the symptom necrosis which also is possible to unlock after skin lesions but we will not evolve necrosis now. These symptoms will significantly increase infectivity of your disease for their cost and actually may from DNA points wise the best symptoms that you can evolve together in a "chain" of symptoms to increase the infectivity of your bacteria.
  • Rash
  • Sweating
  • Skin Lesions
4.)    Now we will evolve the following symptoms as they increase infectivity which again is very important in speed run and costs way less DNA points then would be spent evolving transmissions. These symptoms moderately increase the infectivity and increase the severity of your bacteria.
  • Sneezing
  • Pneumonia
5.) Again we are going to evolve the symptoms that spew your bacteria out of your host which is nausea, vomiting, and diarrhoea. These symptoms will cause a medium increase in infectiousness, medium increase in severity, and a very small increase in lethality which is somewhat bad because it increases the chances of your bacteria being shut out of ports around the world and therefore may lead to some islands being impossible to infect. If this happens feel free to start over but this is necessary as we are trying to get the fastest possible try because we are playing a speed run game.

  • Nausea
  • Vomiting 
  • Diarrhoea
  6.) Next we are going to evolve symptoms which affect the hosts blood except for hyper sensitivity in some way for anaemia we will decrease the red blood cells or haemoglobin in the blood which can lead to the hypoxia into your hosts organs. Hyper sensitivity will lead to distracting the immune system by causing allergic reactions. These symptoms will boost both infectivity and severity.
  • Anaemia
  • Haemophilia
  • Hyper Sensitivity
7.) By the time you completely evolve all of the symptoms that are included in this section "6" you should notice that India should be completely infected if this guide is working properly and effectively. India should begin to spread the bacteria to other countries and cause it therefore to spread around the globe. Do not evolve the transmission extreme bioaerosol yet.
  • Air I
  • Water I
  • Air II
  • Water II
8.) In order to continue the spread of the disease effectively and quickly we will have to evolve these abilities in order for our disease to spread in the varied climates and quality of drugs in the world.

  • Cold Resistance I
  • Drug Resistance I
  • Cold Resistance II
  • Drug Resistance II
  • Bacterial Resilience I
  • Bacterial Resilience II
  • Bacterial Resilience III
9.) At this point feel free to evolve the transmission extreme bioaerosol.
  • Extreme Bioaerosol
10.) Evolve these following symptoms to increase infectivity again and will also boost lethality which will help in the end game but may cause ports to shut down. Again, if that happens feel free to restart the game. This will increase infectivity and lethality.
  • Necrosis
  • Dysentery
  • Pulmonary Oedema
  • Pulmonary Fibrosis
 11.) Wait until all the island countries are infected till you evolve these symptoms. If not all the island countries are infected I would highly recommend you evolve livestock I and livestock II right now. If a country that is in the mainland and is not infected please feel free to evolve these symptoms but you may have to evolve livestock I and livestock II later. The main non-island country you may have trouble spreading your disease is the country of Morocco but the transmissions livestock I and livestock II should take care of the problem when you feel you should evolve it.
  • Total Organ Failure
  • Hemorrhagic Shock
  • Systemic Infection
  • Internal Haeorrhaging
  • Immune Suppression
  • Tumours
  • Fever
  • Inflammation
  • Seizures
11.2) If you haven't evolve these transmissions yet evolve.
  • Livestock I 
  • Livestock II
12.) At this point evolve these symptoms and transmissions
  • Coma
  • Bird I
  • Bird II
13.) Feel free to evolve very infectious transmissions
  • Any Infectious Transmissions
14.) You should at this point win the game and get around 230-280 days if the guide worked properly and you should get 5 biohazards on speed run! Have fun with your new record!

Got any suggestions for this plague or another for the speed run mode? Feel free to add in the comment section below!


  1. Good Luck! Also I would like to note that mutations and random events may cause it to not work.

  2. I think that the best way to play speed run is in the Sovereign Default in the Casual Difficulty

  3. It is an independent mode. It is a seperate gamemode

  4. Normal difficulty: 322 days. I won the achievement "Insane Bolt"!

  5. This strategy also works with Parasite (258) and Prion (245).

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  7. Michael FiorucciMay 4, 2015 at 12:13 AM

    Killed in 288 days with 5 biohazards