Plague Inc. Unknown Origin: Parasite Mega-Brutal(3 Biohazard) Guide

For a list of available plague guides for the Unknown Origin scenario, Click here.

My strategy for the Parasite plague type is just the strategy I used for Bacteria, but with a few small changes. I used the same strategy because Bacteria and Parasite are somewhat the same except for their unique abilities--both of which I really don't see useful, at least in the strategies I use.

Guides for the Parasite plague type in the Unknown Origin scenario could also be used on a normal non-scenario game. This is because this scenario just randomizes which country you start in.

Spicy's Strategy

I have tested this strategy over and over again on a normal game of Parasite in mega-brutal difficulty. It always finishes within 365 days with a cure progression of below 25%.

The suggested starting country for this strategy is India. Although I have never tested the strategy in the scenario itself while starting in India(I spent hours trying to get India as a country), I am quite confident that it'll work extremely well if started in India.

This strategy also works for the following countries:
  • Egypt
    Parasite started in Egypt stats
  • Central America
    Parasite started in C.America stats
The strategy also worked for Iraq and South Africa, but only finished with 2 biohazards mainly because of the late infection of either Greenland or the Caribbean.

Gene Setup:

  • ATP Boost
  • Aquacyte
  • Sympto-Stasis
  • Genetic Mimic
  • Extremophile

1.) Wait for your starting country to be selected. You want to start at either India, Egypt, or Central America--India being the best country to start in. If you're using this strategy for a normal game of Parasite, select India as your origin country.

2.) Evolve the following, in this order, as soon as you can:
  • Nausea
  • Cysts
  • Rash
  • Abscesses
  • Coughing
  • Sneezing
  • Sweating
  • Skin Lesions
  • Pneumonia
  • Pulmonary Oedema
  • Diarrhoea

3.) It would be best to devolve any mutated symptoms to get some extra DNA for evolving, but only do this twice--the third one wouldn't give you any DNA and succeeding ones will cost DNA to devolve. Continue by evolving the following:
  • Water 1 & 2
  • Blood 1 & 2
  • Cold Resistance 1
  • Drug Resistance 1
  • Cold Resistance 2
  • Necrosis
  • Drug Resistance 2
  • Vomiting
  • Hyper Sensitivity
  • Pulmonary Fibrosis
  • Dysentery
  • Insomnia
  • Paranoia
  • Seizures
  • Insanity
  • Paralysis
  • Coma

4.) At this point, you'll have to wait for the complete infection of the world--appearance of the 'no one healthy left' pop-up. You could also proceed sooner, just make sure the whole world is completely red. Once the world is completely infected, continue by evolving the following:
  • Total Organ Failure
  • Hemorrhagic Shock
  • Internal Haemorrhaging
  • Tumours
  • Systemic Infection

5.) Remaining DNA should be allocated towards the evolution of Genetic Re-Shuffles. That's about it, at this point you're just waiting for the complete eradication of humans from the Earth.

Thanks for reading my guide and I hope this has helped you obtain those sweet golden biohazards.
End of Spicy's Strategy

If you guys have any tips or other strategies, post them at the comment section below or send them directly to us. HSG!

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